Seafood Products Due to Nitrofurans

Why FDA issued it

Note: The revision of this Import Alert (IA) dated 11/27/2024 updates the reason for alert and guidance section including the agency contacts. Changes to the import alert are bracketed by asterisks (***). ***Nitrofurans are a class of synthetic antibiotics, very effective against a wide range of bacteria including Gram- positive and Gram- negative bacteria and protozoa. Nitrofurans can be used for treatment for a variety of infections in both humans and animals. The nitrofuran class of drugs include furazolidone, furaltadone, nitrofurantoin, nitrofurazone (also known as nitrofural or furacilin) and nifursol. Nitrofuran parent drugs are rapidly absorbed and metabolized after administration and ingestion to form corresponding tissue bound metabolites. These metabolites have a relatively long half-life and cannot be further metabolized, resulting in higher concentrations remaining in the bo

Quoted from the “Reason for Alert” section of the FDA page for 16-129, mirrored 30 August 2026. The quotation is truncated at the length this copy carries.